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Lesley M Arnold Selected Research

Duloxetine Hydrochloride (Cymbalta)

5/2019Efficacy and safety of duloxetine versus placebo in adolescents with juvenile fibromyalgia: results from a randomized controlled trial.
5/2015A randomized, placebo-controlled, double-blinded trial of duloxetine in the treatment of general fatigue in patients with chronic fatigue syndrome.
6/2013Interpreting effect sizes and clinical relevance of pharmacological interventions for fibromyalgia.
11/2012Efficacy and safety of duloxetine 30 mg/d in patients with fibromyalgia: a randomized, double-blind, placebo-controlled study.
7/2012The effect of duloxetine treatment on cognition in patients with fibromyalgia.
5/2012A framework for fibromyalgia management for primary care providers.
10/2011Early improvement in pain predicts pain response at endpoint in patients with fibromyalgia.
6/2011Improvement in multiple dimensions of fatigue in patients with fibromyalgia treated with duloxetine: secondary analysis of a randomized, placebo-controlled trial.
6/2011Estimation of minimum clinically important difference for pain in fibromyalgia.
12/2010Flexible dosed duloxetine in the treatment of fibromyalgia: a randomized, double-blind, placebo-controlled trial.
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Lesley M Arnold Research Topics

Disease

53Fibromyalgia (Fibrositis)
10/2019 - 02/2002
39Pain (Aches)
10/2019 - 09/2004
9Major Depressive Disorder (Major Depressive Disorders)
11/2012 - 09/2004
7Fatigue
09/2017 - 10/2009
5Nausea
11/2012 - 06/2007
4Dizziness (Lightheadedness)
01/2018 - 09/2008
4Headache (Headaches)
05/2012 - 02/2003
3Sleepiness
01/2018 - 09/2008
3Anxiety Disorders (Anxiety Disorder)
01/2008 - 06/2006
3Binge-Eating Disorder (Binge Eating Disorder)
11/2004 - 11/2002
2Mental Fatigue
05/2015 - 06/2011
2Weight Loss (Weight Reduction)
01/2012 - 02/2003
2Constipation
12/2010 - 08/2010
2Diarrhea
12/2010 - 06/2007
2Bipolar Disorder (Manic Depressive Psychosis)
08/2006 - 06/2006
2Obesity
11/2004 - 02/2003
2Bulimia (Binge Eating)
02/2003 - 11/2002
1Chronic Pain
01/2019
1Peripheral Nervous System Diseases (PNS Diseases)
11/2017
1Postherpetic Neuralgia
11/2017
1Chronic Fatigue Syndrome (Myalgic Encephalomyelitis)
05/2015
1Restless Legs Syndrome (Restless Legs)
06/2014
1general anxiety disorder
06/2014
1Neuralgia (Stump Neuralgia)
06/2014
1Seizures (Absence Seizure)
06/2014
1Edema (Dropsy)
05/2012
1Body Weight (Weight, Body)
01/2012
1Overweight
01/2012
1Hyperhidrosis
12/2010
1Sleep Initiation and Maintenance Disorders (Insomnia)
08/2010
1Mental Disorders (Mental Disorder)
01/2008
1Hypertension (High Blood Pressure)
06/2007
1Weight Gain
06/2007
1Feeding and Eating Disorders (Eating Disorder)
08/2006
1Substance-Related Disorders (Drug Abuse)
08/2006
1Psychotic Affective Disorders
02/2004
1Psychotic Disorders (Schizoaffective Disorder)
02/2004
1Schizophrenia (Dementia Praecox)
02/2004
1Paresthesia (Dysesthesia)
02/2003

Drug/Important Bio-Agent (IBA)

22Duloxetine Hydrochloride (Cymbalta)FDA Link
05/2019 - 09/2004
18Pregabalin (Lyrica)FDA Link
01/2018 - 06/2006
9Milnacipran (Ixel)FDA Link
06/2015 - 06/2010
8Norepinephrine (Noradrenaline)FDA LinkGeneric
08/2010 - 09/2004
7Serotonin (5 Hydroxytryptamine)IBA
06/2010 - 09/2004
4Antidepressive Agents (Antidepressants)IBA
07/2015 - 06/2006
4Serotonin and Noradrenaline Reuptake InhibitorsIBA
07/2015 - 01/2006
3N 30IBA
05/2015 - 11/2002
3Fluoxetine (Prozac)FDA LinkGeneric
04/2012 - 02/2002
2LigandsIBA
10/2019 - 06/2006
2esreboxetineIBA
07/2012 - 08/2010
2Neurotransmitter Agents (Neurotransmitter)IBA
09/2011 - 01/2006
2Calcium Channels (Calcium Channel)IBA
06/2010 - 01/2006
2Gabapentin (Neurontin)FDA LinkGeneric
04/2007 - 06/2006
2Topiramate (Topamax)FDA LinkGeneric
11/2004 - 02/2003
1mirogabalinIBA
10/2019
1aminoalcoholphosphotransferase (AAPT)IBA
01/2019
1Pharmaceutical PreparationsIBA
06/2015
14-amino-4'-hydroxylaminodiphenylsulfone (HADS)IBA
11/2010
1Analgesics (Analgesic Drugs)IBA
11/2010
1Opioid Analgesics (Opioids)IBA
06/2010
1Dopamine (Intropin)FDA LinkGeneric
06/2010
1Biomarkers (Surrogate Marker)IBA
10/2009
1Gallopamil (D600)IBA
09/2008
1Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA
09/2007
1EscitalopramFDA Link
06/2007
1ORALIT (ORS)IBA
08/2006
1Anti-Anxiety Agents (Anxiolytics)IBA
06/2006
1Venlafaxine Hydrochloride (Effexor)FDA LinkGeneric
06/2006
1CalciumIBA
01/2006
1Antipsychotic Agents (Antipsychotics)IBA
02/2004
1Anticonvulsants (Antiepileptic Drugs)IBA
02/2003

Therapy/Procedure

7Therapeutics
09/2017 - 01/2006
2Drug Therapy (Chemotherapy)
04/2009 - 01/2008
1Combined Modality Therapy
05/2012